Management Essay Example | Topics and Well Written Essays - 2500 words - 14

Management - Essay Example First of all it presents the general introduction of the outsourcing and in-sourcing. The technique of outsourcing directs a corporation/ business/Company that contracts with another corporation to proffer services that could or else be carried out through in-house personnel. A lot of huge corporations at the present time outsource employments like that e-mail services, call center servicesas well as payroll. These professions are griped through detach corporations that concentrate in every service, as well as are frequently positioned out of the country (Outsourcing?, 2009). There are a lot of causes that businesses outsource an assortment of employments; on the other hand the majority famous benefit appears to be the information that it frequently accumulates money. A lot of the businesses that offer outsourcing facility and services are capable to carry out the job at significantly smaller amount charges, because they do not have to offer profits to their employees, as well as have smaller amount fixed cost expenses to be anxious about (Outsourcing?, 2009). Outsourcing is contracting out practice, like that manufacturing or product design, to a 3rd party business. The assessment to outsource is frequently prepared in the significance of small price or producing enhanced utilization of efforts and time expenses, forwarding or saving efforts going to at the competencies of a particular industry, or else to destroy more well-organized utilization of information, labor, land, capital, technology as well as resources. Outsourcing turned out to befraction of the industry lexicon all the way through the period of 1980s. It is fundamentally a supply of labor.1 Organizations have attempted to enlarge their competitive recompenses as the industrial revolution. Though, in the fifties and sixties variation as well as financial systems of scale turned out to be the novel movement, and in

Communication Styles Essay Example for Free

Communication Styles Essay What is Communication and Communication Styles? Communication according to Webster Dictionary is defined as a process by which information is exchanged between individuals through a common system of symbols, signs, or behavior (Merriem-Webster). Communication can be verbal and in this day in age text and email. Communication styles are the behaviors in communication that are observed by others. This paper will discuss communication, the four types of communication styles, why communication styles matter and how to improve on them. Four Types of Communication Styles The four types of communication styles include passive, passive aggressive, assertive and assertive. Below you will find the definitions of each: * The Passive Style: Communication is done in an apologetic, timid manner that leads to being disregarded by others. * The Passive Aggressive Style: This style is similar to the passive style in that they hide their real thoughts in feelings but in turn will express these thoughts and feeling indirectly through often negative actions. (e.g. talking behind backs, causing conflicts indirectly, â€Å"getting even† in an indirect manner) (Dr. D. A. Williams and Dr. M. Carey). * The Aggressive Style: This style is characterized by an individual being argumentive, threatening, fighting, and having a tendency to interrupt during conversing. Individuals who communicate in this style have no problems with standing up for themselves and communication just how they feel. * The Assertive Style: This style is the healthiest and most balanced communication style. This style is characterized expression of feelings, self-pride, and self-regard, while at the same time being considerate of others (Dr. D. A. Williams and Dr. M. Carey). Communication styles that can lead to problems are: the aggressive style, the passive style, and the passive-aggressive style (Dr. D. A. Williams and Dr. M. Carey). The disadvantages to the passive communication style you are unable to express your true thought and emotions in the fear of rejection, being misunderstood. These types of communicators often go throughout life feeling out of control, depressed, anxious and little self esteem because they are unable to effectively able to communicate their needs. These types of communicators are often taken advantage of by others because they come off so timid. Those who have an aggressive communication have a tendency to alienate others because of their aggressive style of communication. The aggressive communicator uses belittlement, humiliation, and overall overbearing demeanor to control a conversation and get their message across. Passive aggressive communicators also alienate others. They are often left feeling resentful and powerless because they do not communicate their feelings and allow them to bottle up resulting in anger, stress. Often time’s passive communicators cause conflict with those in their lives because they tend to communicate negative feelings sublimely through their actions. Individual who use an assertive style is far more well adjusted because they have the ability to effectively communicate their thoughts and feelings while considering the feelings of others. Why Do Communications Styles Matter? Having the ability to communicate effectively is very important. The style or way in which we communicate effects the relationships we have throughout life and how others view you. In order to succeed in a career one must be able to communicate effectively. More than ever before, the ability to communicate well determines an employees ability to thrive in todays workplace (Kapusta, M. Ph. D). These people are always in demand (A prime example of this is the recent debate between Mitt Romney and President Obama. During the first debate Romney often interrupted the moderator and the President; he seemed to be communicating in an aggressive style. Those in the media reported that he was not looked upon well by some because of it. Improving Communication Skills In order to improve on your communication styles one must identify your communication style, identify problematic situations, and given you have some areas that could be improved, practice changing your communication skills style (Dr. D. A. Williams and Dr. M. Carey). Many are just not aware of or never even thought about what their communication style is. If you realize that you communicate in a more aggressive style just simply try and be more aware of your tone, body language, and listening skills. If one is educated on this subject and understands the components of all four of the communication styles as with anything else, practice makes perfect. Conclusion As previously stated your communication style can either enhance or negatively affect many aspects of your life. Being able to communicate effectively will avoid conflict and misunderstanding with those around you. Beyond just being aware of your personal communication style and practicing to improve there are several other ways in which you can improve in this area. There are classes available in public speaking and communication and interpersonal skills. So be self aware and ask for feedback from others, your relationships and even your career depends on it. References Dr. D. A. Williams and Dr. M. Carey. Getting the Most Out of Your Interactions with Others.: Use effective communication. Retrieved from http://www.med.umich.edu/painresearch/patients/Communication.pdf Kapusta, M. Ph. D. Why Communication Matters. Retrieve from http://www.studentaffairs.pitt.edu/sites/default/files/PDFsandForms/OCC/WhyCommunicationMatters.pdf Merriem-Webster Dictionary. Communication Definition. Retrieved from http://www.merriam-webster.com/dictionary/common \

Synthesis of Isatin Based Caspase Inhibitors

Synthesis of Isatin Based Caspase Inhibitors DESIGN AND SYNTHESIS OF ISATIN BASED CASPASE INHIBITORS FOR RUTHENIUM CAGING APPLICATIONS KASUN CHINTHAKA RATNAYAKE ABSTRACT Apoptosis is the energy dependent programmed cell death. Improper function of apoptosis could lead to diseases such as cancers, strokes, alziemer’s disease. Caspases are the enzymes involved in the later stage of this process. Peptidyl and non-peptidyl caspase inhibitors have been synthesized recently. One of these non-peptidyl compound classes which consist of pyrrolidinyl-5-sulfo isatins have showed a greater potency against executioner caspases, caspase-3 and -7. According to literature and for further caging studies, two compounds were designed, synthesized and evaluated their inhibition against caspase-3 in this study. The analog in which its N-1 position alkylated with a 4-methyl pyridine moiety (7) showed a higher inhibition than the analog in which its N-1 alkylated with cyanoethyl group (8). Thus, the compound  7  was selected for further caging studies with ruthenium. Chapter 1: Introduction 1.1 Apoptosis and Caspases Apoptosis is the process of programmed cell death. This is a significant cellular process which is directly co-related with embryogenesis, immune system, ageing and various diseases including cancers, stroke, myocardial infarction and neurodegenerative disorders.1 Caspases (cysteinyl dependent aspartate directed specific proteases) are the enzymes involved in the later stage of apoptosis. Caspases are divided to different classes according to their role played in the signaling cascade of apoptosis. Caspases 6, 8, 9 and 10 are involved as initiators and caspases 2, 3 and 7 are identified as executioner caspases in the signaling cascade.2The caspases 1, 4 and 5 are found to be non-active in the cell death process. 1.2 Caspase inhibition and modified isatin sulfonamides as caspase inhibitors Caspases play a significant role in both inflammation and apoptosis. Extensive researches have been conducted on caspases and their functions because they act as potential targets in drug discovery. Various inhibitors of Caspase have been made. These inhibitors could be categorized as non-peptidyl and peptidyl based compounds. A greater selectivity could be achieved when non-peptidyl inhibitors are used for different types of caspases. Isatin sulfonamides have showed inhibition on executioner caspases (caspase-3 and -7) in recent studies. In 2000, Lee and researchers reported the x-ray structure of caspase-3 with an isatin analog, 1-methyl-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1h-indole-2,3-dione (a) bound to the active site of the enzyme (Figure 1).3 Modifying isatin sulfonamide analogues with pyrrolidine groups have shown significant effect on caspase inhibition.4 For example, various pyrrolidinyl-5-sulfo isatins have been shown inhibition to caspases, 3 and 7 (Figure 2). These isatin sulfonamide analogs are modified using structure activity relationships and performed these biological assays. The following isatin sulfonamides have shown to be inhibit caspase-3. The stereochemistry of substituted pyrrolidine moiety, cyclic vs acyclic ring structures and ring sizes have been examined for these inhibition studies (figure 3).5 1.3 Ruthenium complexes for caging applications Ruthenium compounds have been reported as significant candidates for caging applications. Light activation of these metal complexes has been extensively studied. Recently, neuroactive biomolecules as well as small molecular enzyme inhibitors have been reported to be caged with these ruthenium complexes. Spatial and temporal release of these caged molecules upon light activation gives insight to develop new tools that could be used to treat various diseases in biological systems. In this study Ruthenium polypyridyl compounds are used in future studies since they have been considered as excellent candidates for caging application of small molecules. Chapter 2: Results and Data 2.1 General considerations All reagents were purchased from commercial suppliers and used as received. Varian FT-NMR Mercury-400 Spectrometer was used to record all NMR spectra. IR spectra were recorded on High resolution mass spectra were recorded on.Melting points were recorded on .Enzyme inhibition assays were done on 2.2 Designing of Caspase inhibitors Recent studies show that various 5-pyrrolidinylsulfonyl isatins act as caspase-3 inhibitors. Several factors were considered in the designing process of these analogs. First, higher caspase inhibition was considered. Use of specific stereochemistry in the pyrrolidine moiety is important since S-alkoxypyrrolidine is more potent than its R-stereoisomer which shows almost no potency against caspase-3. It is reported that methoxymethyl pyrrolidinyl analogs show higher cell toxicity than phenoxymethyl pyrrolidines, thus methoxymethyl pyrrolidine analogs were chosen for further studies. When considering the Ruthenium caging studies, the chosen analogs should contain a group which has a higher binding affinitiy towards Ruthenium. Therefore, pyridyl and cyano groups were selected to incorporate in these isatin sulfonamide analogs. These groups are chosen to be attached to N-1 position of isatin sulfonamide analog. It has been reported that higher alkyl chain on N-1 position could increase th e inhibition. Therefore 4-methylpyridine and cyanoethyl groups were selected to attach on N-1 position of these analogs and compounds 7 and 8 are designed (Figure 3). 2.3 Synthesis of designed isatin sulfonamide analogs The designed analogs were synthesized using literature and modified procedures5, 6, 7 (Scheme 1). The compound 5 was synthesized as the precursor for the final analogs 7 and 8. The compounds 7 and 8 were synthesized using modified and optimized procedures (Scheme 2 and Scheme 3). 2.4 Enzyme Inhibition Assay Caspase-3 inhibition assay was performed for compounds 6 and 7 according to the literature procedure.2 Compound 6 was found to be more potent (IC50 = .. ) of than compound 7 (IC50 = ..). Thus, compound 6 was selected for further caging studies with Ruthenium bipyridine complexes. 2.5 Experimental 2.5.1 Sodium 2,3-dioxoindoline-5-sulfonate (1) Isatin (10 g, 0.068 mol) was added carefully to a stirred solution of 20% SO3/H2SO4 (20 mL) at -15 °C. The reaction mixture was gently warmed up to 70  °C with stirring. Reaction mixture was stirred at 70  °C for another 15-20 min. The reaction mixture was carefully poured on to crushed ice and let ice to melt and then 20% NaOH was added to the reaction mixture (pH=7). The flask containing reaction mixture was kept in an ice bath to induce precipitation of the desired product. The solid was filtered, washed with ice-cold water and dried to give red-orange crystalline solid. The 1H-NMR data was compared and matched with literature data. Yield: 14.48 g (0.051 mol. 75%) 2.5.2 2,3-dioxoindoline-5-sulfonyl chloride (2) Sodium 2,3-dioxoindoline-5-sulfonate dihydrate (2 g, 70 mmol) was dissolved in tetramethylene sulfone (10 mL) under Argon environment at 60-70  °C and phosphorus oxychloride (3.36 mL, ) was added dropwise. The reaction mixture was stirred for 3 h. The reaction was cooled to room temperature and kept in an ice bath. Then ice-cold water was added to the reaction mixture carefully. A precipitate was formed, filtered, washed with ice-cold water and dried used without further purification. The desired compound is yielded as a bright yellow solid. The 1H-NMR data was compared and matched with literature data. Yield: 1.58 g (64 mmol, 92%). 2.5.3 Tert-butyl (S)-2-(methoxymethyl)pyrrolidine-1-carboxylate (3) To a solution of N-Boc-L-prolinol (5.0 g, 25 mmol) in THF (25 mL) at -78  °C, Sodium hydride (60% in mineral oil) (960 mg, 40.0 mmol) was added and stirred for 10 min. Then methyl iodide (2.65 mL, 42.5 mmol) was added dropwise and reaction was stirred for 4h at -78  °C and additional 16 h at RT. Then NH4Cl was added until all H2 evolved and EtOAc was added. The organic layer was washed with water and sat. NaCl, dried over anhyd. Na2SO4 and concentrated to give a pale yellow oil and purified with petroleum ether: ether (9:1) to give a colorless oil. The 1H-NMR data was compared and matched with literature data. Yield: 4.986 g (23.16 mmol, 92%) 2.5.4 (S)-2-(methoxymethyl)pyrrolidine (4) To a solution of tert-butyl (S)-2-(methoxymethyl)pyrrolidine-1-carboxylate (4.98 g, 23.07 mmol) in DCM (40 mL), TFA (25 mL) was added dropwise over 30 min at 0  °C. The reaction was warmed to RT and stirred for additional 1.5 h. The reaction mixture was added to 150 mL of 10% NaOH solution and extracted with DCM (50 mL x 3), dried over anhyd. Na2SO4 and concentrated to obtain a pale yellow oil. The 1H-NMR data was compared and matched with literature data. Yield: 2.657 g (23.07 mmol, 100%) 2.5.5 (S)-5-((2-(methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione (5) The compound (1) was synthesized according to procedure reported by Harvan et al.1 To a stirred solution of 2,3-dioxoindoline-5-sulfonyl chloride (2 g, 8.153 mmol) in 1:1 THF/CHCl3 (80 mL), a solution of (S)-2-(methoxymethyl)pyrrolidine (1.033 g, 8.968 mmol) and DIPEA (2.84 mL, 16.310 mmol) in CHCl3 was added dropwise under Argon environment and stirred for 1 h at 0  °C. The reaction stirred for additional 1 h at RT. The reaction mixture was concentrated and purified using 1:1 EtOAc:Petroleum ether and isolated as bright yellow crystals. The 1H-NMR data was compared and matched with literature data. Yield: 1.185 g (36.53 mmol, 45%) 2.5.6 4-(bromomethyl)pyridine hydrobromide salt (6) Pyridin-4-ylmethanol (5.0 g) was dissolved in 48% HBr (50 mL) and refluxed for 24 h. (Reaction was monitored for completion using TLC). The reaction mixture was concentrated in vacuo until a thick gum appeared and treated with absolute Ethanol at 5  °C. The white crystalline solid obtained was filtered and washed thoroughly with cold absolute Ethanol. The 1H-NMR data was compared and matched with literature data. Yield: 4.74 g (18.7 mmol, 41%) 2.5.7 (S)-5-((2-(methoxymethyl) pyrrolidin-1-yl)sulfonyl)-1-(pyridin-4-ylmethyl)indoline-2,3-dione (7) To a stirred solution of (S)-5-((2-(methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione (1) (168 mg, 0.518 mmol) in DMF, 60% NaH in mineral oil (51.8 mg, 1.295 mmol) was added at 0  °C under Argon atmosphere. The reaction was stirred for 30 min. Then a solution of 4-Bromomethyl pyridine (130.6 mg, 0.518 mmol) in DMF was added dropwise and stirred for 4 h at 0  °C. The reaction was diluted with EtOAc and washed with saturated NaCl (20 mLÃâ€"3). The organic layer was dried over anhyd. Na2SO4 and concentrated in vacuo. The crude product was crystallized using EtOAc:Hexanes and isolated as a yellow solid. Yield: 85.8 mg (0.207 mmol, 40%) mp = 172-174  °C, 1H NMR (400 MHz, CDCl3): ÃŽ ´ 8.64 (d, 2H, J = 6 Hz), 8.11 (s, 1H), 8.03 (d, 1H, J = 8.4 Hz), 7.27 (d, 2H, J = 3.6 Hz), 6.83 (d, 1H, J = 8.4 Hz), 4.99 (s, 2H), 3.74 (m, 1H), 3.55 (dd, 1H, J = 9.6 Hz, 4 Hz), 1H NMR (400 MHz, DMSO): ÃŽ ´ 8.51 (d, 2H, J = ..Hz), 8.01 (d, 1H, J = Hz), 7.84 (s, 1H), 7.46 (d, 2H, J = Hz), 7.07 (d, 1H, J = Hz), 4.99 (s, 2H), 3.67 (m, 1H), 3.41 (dd, 1H), 3.24 (s, 3H), 3.06 (m, 1H), 1.73 (m, 2H), 1.48 (m, 2H) 13C NMR (100 MHz, CDCl3): ÃŽ ´ 183.2, 160.8, 152.5, 150.5, 137.5, 134.9, 124.9, 122.1, 117.5, 110.8, 74.8, 59.2, 59.1, 49.3, 43.3, 28.8, 24.1 IR (ÃŽ ½max) (KBr): 3443, 2929, 2361, 2342, 1747, 1616, 1478, 1450, 1417, 1365, 1344, 1330, 1199, 1181, 1154, 1130, 1115, 1070, 1041, 994 MS (HRMS): 432 (M+Na+MeOH)+, 400 (M+Na)+ 2.5.8 (S)-3-(5-((2-(methoxymethyl) pyrrolidin-1-yl)sulfonyl)-2,3-dioxoindolin-1-yl)propanenitrile (8) To a stirred solution of (S)-5-((2-(methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione (1) (200 mg, 0.620 mmol) in DMF (10 mL), KOH (4 mg, 0.062 mmol) was added and stirred for 10 min at RT. Then acrylonitrile (45  µL, 0.680 mmol) was added dropwise and stirred for 2 days under Argon environment at RT. The reaction mixture was added to H2O (30 mL), and extracted with EtOAc (20 mLÃâ€"3). The combined organic layer was washed with 10% NaCl (20 mLÃâ€"3). The organic layer was dried over anhyd. Na2SO4 and concentrated in vacuo. The crude product was purified with CH2Cl2: MeOH (99:1) to afford yellowish-orange solid. Yield: 63.6 mg (0.169 mmol, 27%) mp = 134-138  °C, 1H NMR (400 MHz, CDCl3): ÃŽ ´ 8.15 (d,1H,J=Hz), 8.11(d,1H, J=.Hz), 7.18(d,1H,J=.Hz), 4.10 (t,2H,J=), 3.77(m,2H), 3.57(dd, 2H, J= Hz), 3.43(m,H), 3.40 (s,..H), 3.38(d, H, J=Hz), 3.36 (s,3H,), 3.14(m,H), 2.98,2.96,2.94, 2.86(t,2H, J=Hz), 2.04(s,..H), 1.92(m,H), 1.69 (m,.H), 1.55(s,H) 13C NMR (100 MHz, CDCl3): ÃŽ ´ 180.8, 157.8, 152.3, 137.6, 134.7, 124.9, 117.5, 116.8, 110.4, 74.8, 59.3, 59.1, 49.4, 36.8, 28.8, 24.1, 16.7 IR (ÃŽ ½max) (KBr): 3422, 2921, 2852, 2361, 2251, 1742, 1717, 1647, 1612, 1558, 1542, 1508, 1475, 1456, 1418, 1373, 1364, 1340, 1314, 1268, 1234, 1195, 1175, 1153, 1133, 1063, 1046, 991, 970, 905, 877 MS (HRMS): 470 (M+Na+MeOH)+ Chapter 3: Conclusion and Future directions The compounds 7 and 8 were both potent for caspase-3 but compound 7 show more inhibition than that of compound 8. Thus compound 7 was selected for further ruthenium caging studies. The caged ruthenium complexes could be subjected for light activation experiments where IC50 of this complex under light and dark conditions could be determined and the dark to light inhibition ratio could be explored. Then cell toxicity studies could be done in order to explore the ability of these ruthenium complexes for prevention of apoptosis in biological systems. These combined experiments and results could lead to the final goal of this research study which is the development of novel tools to prevent apoptosis in biological systems.

Observing the Positive Side of the Medical Profession Essay -- Medical

People who decide to become medical doctors need to make several sacrifices. The training to become a doctor is long and difficult. Furthermore, it does not end with school because doctors are required to learn about new problems and advances in the field of medical science for the rest of their lives. However, there is a positive side in becoming a doctor. It is not just about learning complicated procedures and going through rigorous training. Being a doctor means that a person is required to nurture the positive fundamental characteristics of the human mind. Doctors have to be truthful, both to their patients and their patients' relatives. They need to be above discrimination. If a doctor practices medicine with a correct attitude and respect towards the oaths taken, that person has an opportunity to develop all positive qualities of a human being and improve people's living standards without sacrificing their own. Becoming an expert in the field of medicine is a long process that will turn away most people, particularly because doctors gain their abilities exclusively by practicing on other people. â€Å"The moral burden of practicing on people is always with us, but for the most part unspoken† (Gawade, 2003). Besides the moral burden that is created by practicing on others, when their lives might depend on the doctor's skills, doctors need to constantly keep up with the advances in the field. In addition, they need to adapt to different patients constantly. Even if there are no advances in the medical field, the doctor must always remain flexible and accept that something unexpected might happen at any given moment. Atul Gawade (2003) states that the incredible pace of advances in medicine do not always keep up with the advances... ...cause no other field is so closely connected to human well-being and life. However, according to Carola Eisenberg (1986), â€Å"What we do as doctors, most of the time, is deeply gratifying, whatever the mix of patient care, research, and teaching in our individual careers. I cannot imagine a more satisfying calling. Let us make sure out students hear that message from us†. In the final part of the UCLA medical oath, the doctor states, â€Å"In being true to this oath, I will preserve the finest traditions of medicine and science, and enjoy and conduct my life, my profession, and my art to the fullest† (Robinson & Parker, 1995). Doctors do not give up their lives to help others. Doctors swear that they will live their life and art to the fullest. And there is no greater satisfaction in life other than when a person lives both his professional and personal life to the fullest.

Difference Between General Perspectives :: essays research papers

What is the difference between the general perspectives? How does the work of Ritzer attempt to overcome this problem? Micro theories examine the processes of face-to-face contact among individuals and personal points-of-view in society; whereas, the macro theories deal with large-scale social events of society - meaning things that have public concern. The theories that are apart of the micro-level are symbolic interactionism, dramaturgy, ethnomethodology, and exchange theory. Symbolic interaction is an individual-based theory that uses constructed symbols, such as language and gestures, to which people give meaning in their everyday interactions. Dramaturgy, best stated by Goffman (1959), is what actors portray on a the theatrical stage is similar to the way people act in society. Ethnomethodology is basic common-sense used in for general situations in everyday life (Ritzer, 77). Exchange theory is a given relationship is found to be attractive whereas the rewards tend to outweigh punishment (Blau, 1964). Structural functionalism and conflict theory are two types of macro-theories. Structural functionalism (Perrucci, 1983) has three main ideas: 1) society is a system containing interdependent and interacting parts bound together in time and space, 2) shared values among members of the system are social â€Å"glue† that helps hold it together, 3) and systems have a need for stability and therefor attempt the parts working together harmoniously. Conflict theory is the belief that society contains basic inequalities in wealth, power, and prestige (Coser, 1967; Dahrendorf, 1959). Ritzer, like many other sociologists, wants to disintegrate the split between the micro and macro sociology. Ritzer attempts to do this by â€Å"adding on† to Gurvitch’s insights . Ritzer views the micro-macro issue, not by subjective-objective continuum, but the phenomena as subjective or objective; therefore, concluding that there are four major levels of analysis (See Table I) that are a product of dialectical interrelationships (Ritzer, 1996). Table I - Ritzer’s Major Levels of Social Analysis MACROSCOPIC I. Macro-objective Examples - society, law, bureaucracy, architecture, technology, and language  Ã‚  Ã‚  Ã‚  Ã‚   II. Macro-subjective Examples- culture, norms, and values III. Micro-objective Examples - patterns of behavior, action, and interaction  Ã‚  Ã‚  Ã‚  Ã‚   IV. Micro-subjective Examples - perceptions, beliefs; the various facets of the social construction of reality MICROSCOPIC In row 1, the macro-objective, involves the large-scale basic standards and â€Å"material realities† (Ritzer, 359) by which the general populous abides by; whereas as the macro-subjective is the large-scale intangible ideals such as norms and values which shape our everyday lives. In row 2, the micro theories also have the objective and subjective consistencies but on a smaller scale.

Types of Parents and the Type of Parent I Am Essay -- parenthood, raisi

There are many types of parents in the world today. The types of parents could be classified in many different categories. I believe there are three types of parents today: the Consultants, the Helicopters, and the Drill Sergeants. In this essay, I will discuss and explain each of these types of parents. I will also discuss the type of parent I believe I am, and how my parenting style may affect my children in the future. The Consultant Parents is a loving and logical parent that provides guidance and consultant services for children. They provide messages of personal worth and strength and rarely mention responsibilities. The Consultant Parents demonstrates how to take care of self and be responsible. They share personal feelings about their own performance and responsibilities with their child. The Consultant Parents provides and helps their child explore alternatives and then allows the child to make his/her own decision. They provide the child with a â€Å"time frame† to complete their responsibilities. The Consultant Parents often uses lots of actions and very few words. They allow their child to experience life’s natural consequences and allow them to serve as the teacher. The Helicopter Parents hovers over their children and rescues them from the hostile world in which they live. They provide the messages of weakness and low personal worth. The Helicopter Parents tends to make excuses for the child, but complains about the child’s mishandles responsibilities. They take on their child’s responsibilities and protect the child from any possible negative feelings. The Helicopter Parents will make decisions for the child and provides no structure, but complains to the child saying, â€Å"After all I’ve done for you†¦Ã¢â‚¬  The Helicop... ...g or almost doing and their parents do not do things for them that satisfy their own needs rather than the needs of the child. Therefore, in conclusion, there may be many types and styles of parenting today, my classifications for parenting types are three categories: the Consultants, the Helicopters, and the Drill Sergeants. Each of these three parenting styles has their positive and negative aspects. I choose to incorporate a mixture of each style in the parenting and raising of my children. My style of parenting seems to be working very well thus far. I will have to continue in my parenting life and see how my parenting style will affect my children in their futures. Works Cited Banks, E. (2014). Toddler Discipline - The Parent's Guide To Toddler Discipline. Speedy Publishing. Levine, M. (2012, August 4). The New York Times. Raising Successful Children.

Different World Markets Essay

It is commonly accepted that marketing strategies play very important roles in most international organizations. Some believe that a company which plans to expand its business and want to be a successful international firm should have very effective marketing strategies. As a number of writers (John, Letto-Gillies, Cox and Grimwade 1997, Ketelhohn 1993, Johnson and Scholes 2002) have pointed out, international marketing strategy is concerned with making important policy decisions affecting the long-time direction of the company. This paper first proposes the importance of international company’s marketing strategy, and then considers how to make a competitive marketing strategy and carry out it in a right way. After that, it will look at how to understand ‘change’ in business environment and what organizations should pay attention to in a changeable market. In the final part, it will focus on a specific international company’s global marketing strategy. Importance of international marketing strategy. Over the years, many definitions of ‘marketing strategy’ have been made and developed, a typical definition was made by Quinn (cited in John, Letto-Gillies, Cox and Grimwade, 1997) who describes marketing strategy as: †¦ the pattern or plan that integrates an organisation’s major goals, policies and action sequences into a cohesive whole. A well-formulated marketing strategy helps to marshal and allocate an organisation’s resources into a unique and viable posture based on its relative internal competencies and shortcomings, anticipated changes in the environment and contingent moves by intelligent opponents. (Quinn 1980:pp3) According to John, Letto-Gillies, Cox and Grimwade (1997), although there were many definitions about marketing strategy, most of them emphasize the same direction in which the organization is developing, where the organization is going, where the organization is or where it should be. In fact, problems mentioned by them are the biggest headache and trouble maker for most international enterprises, thus marketing strategies enable  companies to find out how and where to develop. As Hill (2005) sees the marketing strategy in international business, nowadays, process of the global economy and liberalization of investment environment result in many global markets becoming extremely competitive, in order to get more profit in such an international environment, a company should have a very clear marketing strategy which cares a lot about its position. In all models of marketing strategies, international marketing strategy is a very large part and it affects other part of strategies to a international company in a certain degree. As Manu (1992) has pointed out, more and more organizations take the whole world as their market with the quickening process of globalization in the past decades, the role and effective marketing strategies in different geographic market-places become a greater need for them to analyse caused by the growth in the globalization of business and markets. All these indicate that marketing strategies do have important influence on international enterprise’s performance; therefore an effective marketing strategy cannot be ignored when companies plan to expand their business. How to make a competitive marketing strategy. From the very start, how to make a competitive marketing strategy is always the problem which international companies have to face. As Ketelhohn (1993) has pointed out, a strategic analysis is the most important of all; it starts by setting the generic strategies which are hypotheses in the industry and finding out the main success factors which are related to each strategy. Then consulting teams in the company should check their understanding of those marketing strategies by comparing them with documented facts. Once they are satisfied with those marketing strategies which they think fit their enterprises’ capabilities, they are able to choose consultants and build strengths in key success factors in which the firm is weak by recommending investment projects. All these details should be considered into companies’ marketing strategies, after planning and making marketing strategies, the next important step is taking those marketing strategies into action and managing them in a right way, good strategic management is not only related to one department, but the  responsibility of the whole company, as Johnson and Scholes (2002) see it, ‘marketing strategy is about how organizations perform overall. Since very few individuals sit at the very top of organizations, their experience of, and contribution to, strategic success is from â€Å"below†. They will operate in parts of an organization where their day-to-day work is dominated by issues about that function’. According to them, enabling the success of marketing strategy in action should from the very top managers to individuals lower down as resources and competences which are crucial in this process are controlled by them. ‘Change’ in business environment. Change is accepted widely in our modern life, it also exists in the business environment all the time, according to the research of Drummond, Ensor and Ashford (2003), ‘the phrase â€Å"change is the only certainty† has become something of a business mantra. All organizations are subject to increasing levels of change.’ Actually, every change exists in the market has the original factor which concerned with the environment where international organizations carry out their marketing strategies, Carter (2002) identifies those factors as political factors, economic factors, technological factors, social or cultural factors, legal factors and competitive factors. It is very important for international companies to full understand these various factors and identify the most important kinds of factors which may influence the company and its consumers’ relationship when they carrying out foreign marketing strategies. Peugeot Company was established in France in 1890 and now it has become one of the ten biggest car manufactures in the world. In order to explore the market, Peugeot invested in Guangzhou, China, in 1985, it failed and left China in 1997. The main reason is lack of competitiveness of its products. On the other hand, Dongfeng Peugeot was created in China. From the external environment, four pieces of information are very clear: firstly, China entered into WTO and then cut its tariffs on auto imports. Secondly, China’s car market is booming. Thirdly, personal incomes are increasing. Finally, more competitors are entering into China’s market. By analysing and  summarising Peugeot’s marketing strategies, there are four main marketing strategies related to its operations: firstly, Peugeot tries to improve the quality and design and find out the acceptance of Chinese marketplace. Secondly, it cuts prices to boost sales. Thirdly, it offers an effective on-line sale channel. Finally, it tries to improve customer service all the time. In conclusion, there is no doubt that marketing strategy plays a crucial role in international enterprises. Making an effective global marketing strategy is a good beginning, carrying out the marketing strategy in a proper way is very essential in the globalization process, understanding the market’s change and identifying problems which is related to a company are also very important in carrying out the marketing strategy. All these steps are linked with one another; they are key points relating to the marketing strategy which is really necessary in international organization. References: Cater, S (2002) International marketing strategy. London: Elsevier Science Ltd. Drummond, G., Ensor, J,. and Ashford, R (2003) Strategic Marketing Planning and Control. London: Butterworth-Heinemann Publications. Hill, C.W.L (2005) International Business. New York: The McGraw-Hill Companies. John, R., Letto-Gillies, G., Cox, H., and Grimwade, N. (1997) Global Business Strategy. London: International Thomson Business Press. Johnson, G. and Scholes, K (2002) Exploring Corporate Strategy. Edinburgh: Pearson Education Limited. Ketelhohn,W(1993)International Business Strategy.London: Butterworth-Heinemann Ltd. Lasserre, P (2003) Global Strategic Management. New York: Palgrave Macmillan Houndmills. Manu, F.A. (1992), â€Å"Innovation Orientation, Environment and Performance: A Comparison of U.S. and European Markets,† Journal of International Business Studies, 23 (2), 332-59.